Immune Consequences of Chlamydia Infections in Pregnancy and In Vitro Fertilization Outcome

Chlamydia trachomatis Infection, Immunity, and Pregnancy Outcome

Chlamydia trachomatis can ascend from the cervix to the fallopian tubes and survive for long periods of time without causing symptoms. The immune response to infection clears the extracellular organisms but leads to development of a persistent intracellular infection. Repeated cycles of productive infection and persistence eventually induce tubal occlusion and infertility. Persistently infected...

Immunity to heat shock proteins and pregnancy outcome.

Heat shock proteins are among the first proteins produced by the zygote after fertilization. In addition, the maternal decidua also expresses heat shock proteins during the early stages of pregnancy. Autoimmunity to heat shock proteins is not typically evident in healthy women of reproductive age. However, a chronic microbial infection, such as an asymptomatic Chlamydia trachomatis upper genita...

Relationship between Endometrial Thickness and In Vitro Fertilization-Intracytoplasmic Sperm Injection Outcome

O-32: Effects of Intrauterine Injection of Recombinant Human Chorionic Gonadotropin before Embryo Transfer on Outcome of In Vitro Fertilization/Intracytoplasmic Sperm Injection: A Randomized Clinical Trial

Background: To evaluate the effectiveness of intrauterine injection of recombinant human chorionic gonadotropin (rhCG) before embryo transfer (ET). Materials and Methods: In this randomized placebocontrolled clinical trial, a total number of 182 infertile patients undergoing their first in vitro fertilization/intracytoplasmic sperm injection (IVF-ICSI) were randomly assigned to receive 250 μg i...

History of Chlamydia Trachomatis Infection Threatens Fertility in Women with Unilateral Tubal Occlusion

Tubal factors are associated with infertility. To evaluate the influence of past Chlamydial infections on female fertility with unilateral tubal occlusion, we compared the cumulative pregnancy rate of Chlamydia antibody seropositive women with those who are seronegative. A retrospective, case-controlled study was designed. A total of 54 consecutive infertile women with unilateral tubal occlusio...